
7d - National surveillance system for invasive Haemophilus influenzae disease in Italy: evaluation of completeness and timeliness, 2016–2022
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Background : The Italian national surveillance system (NSS) for vaccine-preventable invasive bacterial illnesses has monitored invasive Haemophilus influenzae disease (HID) since 2007. Except for a sensitivity analysis in 2016, the HID-NSS has never been evaluated before. We evaluated the completeness and timeliness of the HID-NSS in Italy from 2016 to 2022.
Methods : We analysed HID cases reported to the NSS from 2016 to 2022 and measured completeness and timeliness per year, at national and regional level. Completeness was assessed as the percentage of missing data for: place and date notification, age, sex, vaccination status, comorbidities, infection type, serotype, place and date symptoms onset, outcome and sequelae. Timeliness was assessed as the time between symptom onset and first notification.
Results : 969 cases were notified between 2016 and 2022. The number of cases reported in 2020 and 2021 (94 and 65) was substantially lower than in other years (162 cases/year average). Place and date notification, date symptoms onset, comorbidities, sequelae, and infection type were complete; age and sex ranged from 97% to 100% annually. Completeness per year in vaccination status (range=39-72%), place symptom onset (47-87%), outcome (45-72%) and serotype (58-82%) improved or remained relatively stable over time. Depending on the reporting region, completeness in place symptom onset, outcome, and serotype was between 0% and 100%. The timeliness of reporting improved from 2016 to 2022 with an overall median of 7 days (IQR=3-21). Timeliness also varied substantially per region (median=3-27 days depending on region).
Conclusions Our analysis identified gaps in crucial variables, and differences in both completeness and timeliness over time and across regions. Reducing the number of variables, and follow-up information sessions in regions with incomplete and untimely reporting may be beneficial.